The aim of this study was to investigate the STRUCTURAL relationship between perception of LEARNING environment AND academic burnout through mindfulness. Three hundred AND five female students were selected from Yasuj high schools using multi-stage rANDom sampling. The participants completed the Perception of LEARNING Environment (Sweeney, Sorensen, & Kemis, 1994), the Toronto Mindfulness Scale (2006), the Academic Burnout Questionnaire (Breso, Salanova & Schoufeli, 2007). The results indicated that the model had a good fitness with the data. There were direct effects of perception of LEARNING environment on academic burnout, mindfulness on academic burnout, AND perception of LEARNING environment on mindfulness. The perception of LEARNING environment had a slight effect on academic burnout through mindfulness. The findings suggested that perceptions of LEARNING environment enhance meta-cognitive processes AND the conscious mind by making students to engage in LEARNING, having a sense of ownership in the classroom AND doing homework effectively. Thus, increasing capacity of attention, flexibility AND acceptance prevent academic burnout.